The presence and regulatory role of endocannabinoid system in all animals has been confirmed by the scientific studies. Both humans and animals produce endocannabinoid, that can act on specific receptors that are found all throughout the body. These endocannabinoids regulate the various physiological roles we have day to day. While in a diseased state, the activation of those receptors with phytocannabinoids could be helpful in threating the underlying problems. But if we want to treat various medical problems in a non toxic way, then we want to push for more research in cannabidiol (CBD).
You may wonder if you should consider giving CBD to your beloved dog, or family pet? Does it work? Is it really safe?
Yes, it works safely for various medical conditions!
While Tetrahydrocannabinol (THC), may be harmful for pets and cause psychoactive effects, no study has ever been reported for CBD being harmful to pets, but can be very beneficial to pets in many ways. Not all, but most of the edible canine cannabis treats on the market are virtually THC-free. This means that the treat is completely non-psychoactive and non-toxic for pets. A large amount of pet edibles are derived from hemp, instead of marijuana, also due to legal issues right now. While companies are not making any therapeutic claims against CBD, these veterinarians still have been dealing with legalizations. That being said, there are still a low amount of issues when selling CBD infused edibles made for pets.These edibles can safely treat inflammation, pain, cancer-related health problems, and can also be used for palliative care or end-of-life ailments.
No one really wants to see their four-legged companion suffering from an illness, suffering from inoperable or late stage cancer, or having severe arthritis. These types of painful conditions can prevent your pets from eating, while also suffering from muscle loss. For many years, canine diseases have been typically treated with various synthetic veterinary drugs. Much like Rimadyl, synthetic drugs can cause moderate to serious side effects which are also in many veterinary pain medications, as well as human pain medications. These certain drugs can cause liver and kidney damage, and these drugs are still being prescribed by veterinarians. While we are still being left with the no way of prescribing pets with CBD. They’re purchasing CBD-laced edible treats to relieve their pet’s problems.
Many veterinarians are not ready to use CBD products as medication for pets, but many pet owners are not willing to stand by and wait anymore. They’re purchasing CBD-laced edible treats to relieve their pet’s problems.
And the feedback could be any better, pet owners have vouched for the use of CBD treats to help soothe anxious dogs, particularly in cases dealing with separation anxiety, thunderstorm fears, traveling in cars, anxiety during veterinary visits, and social anxiety in canines.
Pharmacokinetics of CBD in dogs
Due to the legal restrictions in the United States, veterinary researchers have studies to optimize safe and effective doses of CBD for various medical conditions, but are stating that they are quite difficult to conduct. These studies can become very expensive, and the available pharmacological data on animals using CBD is scarce. Unlike humans, dogs metabolize cannabinoids in a different way.
In dogs, 2-AG and anandamide are the primary messenger cannabinoids. These chemicals activate CB1 and CB2 receptors in the brain and other regions, respectively. Being an agonist to these receptors, CBD weakly binds to these receptors for a longer duration, and evokes long-lasting therapeutic response without causing toxic effects.
After intravenous infusion, CBD distribution was reported to be rapid, followed by prolonged elimination with a terminal half-life of 9 hours. The total body clearance may take up to about 17 hours after administration. The oral bioavailability appears to be low (13-19%), which may be due to the first pass effect in the liver. With low bioavailability, the risk of developing systemic toxicity may be low in dogs.
Once the effects wane, the dog’s liver metabolizes the cannabidiol and eliminate it via the urine or bile in a sustained and safe manner. This might be the possible reason for achieving immediate but prolonged therapeutic response in CBD-treated animals.
Claims that Support CBD Use in Pets
Like many humans uses, the veterinary marijuana use has really caught the scientific community’s interest, and safe to say the interest of most of the general public lately. Unfortunately, cannabis still remains a Schedule I drug. Thats why clinicians, medical and veterinary researchers have been feared to conduct a more collaborative research study.
Although that might be, encouraging researchers find evidence that is now surfacing in hopes to gain public acceptance. While several independent organizations are demanding for medical marijuana legalization across the globe. Marijuana advocates have petitioned the Drug Enforcement Administration to consider rescheduling marijuana, which has been unsuccessful thus far.
It is sad to say at this time, the number of human research studies that have been underway in exploring the potential medical benefits of cannabis, are not appreciable. It may take at least half a decade to see promising veterinary cannabinoid research results. So until that is fixed, we then have to turn and rely on anecdotal evidence and testimonials of many pet owners. It has been proven that animals share 70% biological homology with humans. So we have some grounds to believe that cannabis could be useful for treating canines.
For a few, it is a surprise to see an massive amount of favorable testimonials that further support veterinary cannabinoid use. Even on the AVMA website. The AVMA had published testimonials of pet owners who endorse cannabis use, and who claimed its uses had dramatically impoved the quality of their pets life. Signs of better mobility when previously unable to ambulate. It has shown signs to improve appetite and reduce the reliance on conventional medications, especially when focusing on animals that are intolerant to those synthetic drugs.
In one study, they have found that the endocannabinoid system and cannabinoids could prevent immune-mediated and inflammatory allergic disorders. This study included skin problems for dogs. Another study had concluded that CBD has anticonvulsant and anti-epileptic properties. These are compared to the conventional anticonvulsant drugs like Phenytoin and Phenobarbital.
AHVMA reported in a study, that a 61.8% to 95% of pet owners have endorsed the healthy benefits of CBD treats that are in the moderate to excellent range.Some of the medical conditions that were relieved by these edible treats include pain, nervous system problems, inflammation, anxiety, nausea and/or vomiting, digestive system problems, tumors, seizures/convulsions, skin problems and phobias, including fireworks or thunderstorm phobias.
A large amount of our community is well aware that cannabinoids can alleviate rheumatoid pain in humans. However, dogs do not suffer from rheumatoid arthritis but can suffer from osteoarthritis (OA). This is a bone and joint disease that can occur from the result of the joints wear and tear. OA can causeneuropathic pain, for which cannabinoids can be helpful.
Both the research evidence and the testimonials of the pet owners appear to be encouraging.
- Julianna hated to see her beloved dachshunds suffer with painful disc problems and side effects, even after unsuccessful treatments with Tramadol and Rimadyl. She chose to treat her dogs with CBD-infused oil. After few weeks, the mood and mobility of the dogs improved without any notable side effects.
- One pet owner acknowledged the anti-convulsive benefit of CBD and his dog’s epileptic episodes have reduced to one per month after cannabis treatment.
- One California-based pet owner has said that CBD has significantly improved the health of his dog after an injury.
- David Bourgouin’s dog suffered traumatic injury between the chest and the leg. The injury caused a large cyst that limited the dog’s mobility and surgery was recommended by the veterinarian. Due to the high cost of surgery, David opted to treat his dog with CBD and the results were amazing. After a few weeks, the dog has been able to run without any signs of persistent pain.
The American Medical Association, is within the midsts of urging to reschedule marijuana with the Federal Government. Eventhough it is legal in some states. Full legalization would be helpful to conduct veterinary research and to develop cannabinoid formulations. Like the AMA, the AVMA has called veterinarians for scientific debate on this issue, which is noteworthy.
Needless to say, CBD is one the greatest natural gifts this world has to offer, and not just for humans, but for our pets as well. Even though CBD is not a cure all medication, it can ease the pet’s discomfort, relive debiliting pain and extend their lives. By opting for CBD, pet owners need not turn to euthanizing their pets to end their pets’ suffering.
What are your thought on this subject?